1
TI: Reduction of seizure frequency with clomipramine in patients with complex partial seizures.
AU: Sakakihara-Y; Oka-A; Kubota-M; Ohashi-Y
SO: Brain-Dev. 1995 Jul-Aug; 17(4): 291-3
PY: 1996
AB: Two patients with complex partial seizures who had been refractory to various antiepileptics were treated with clomipramine. The frequency of the seizures was reduced to 0-30% of the original levels. It has been reported that imipramine is effective in absence and minor motor seizures, and its antiepileptic effect is thought to be related to the inhibition of the presynaptic re-uptake of serotonin and norepinephrine. The basic effect of clomipramine is the same as that of imipramine except that the inhibitory action of clomipramine on serotonin re-uptake is 5- to 10-times more potent than that of imipramine. It is implied that clomipramine may be of use in the treatment of partial epilepsies.
2
TI: Use of the internal jugular vein approach in balloon dilatation angioplasty of pulmonary artery stenosis in children.
AU: Senzaki-H; Koike-K; Isoda-T; Ishizawa-A; Hishi-T; Yanagisawa-M
SO: Pediatr-Cardiol. 1996 Mar-Apr; 17(2): 82-5
AB: Generally, the approach used for balloon dilatation angioplasty for pulmonary artery stenosis in children is from the femoral vein. However, sometimes an alternative approach must be used because of femoral vein occlusion or some other reason. As reports have been limited about the results achieved using the internal jugular vein approach in pediatric interventional catheterization, we report on the internal jugular vein approach in balloon dilatation angioplasty of the pulmonary artery for pediatric patients and discuss the advantages of this approach. From 1991 through 1993 15 balloon dilatation angioplasties of the pulmonary artery using the internal jugular vein approach were performed in 14 pediatric patients, ranging in age from 4 months to 13 years. Based on this experience, we have evaluated this method from several viewpoints including the technique and possible complications. All procedures were performed without complications in all patients; and by inserting a 7 sheath it was even possible to perform balloon dilatation in a 4-month-old infant. A sheath as large as 9F could be inserted in other patients, and the double balloon method was used in seven patients. The Seldinger method was also available when the balloon catheter was too large to use with a sheath. For pediatric interventional cardiac catheterization, it was found that the internal jugular vein approach is relatively safe and reliable. Furthermore, catheterization of the pulmonary artery was easier with the internal jugular vein approach than with the femoral vein approach.
3
TI: Neurally mediated syncope complicated with paroxysmal atrial fibrillation.
AU: Kato-H; Masutani-S; Hoshiyama-M; Shibuya-K; Isoda-T; Hishi-T; Murakawa-Y; Yanagisawa-M
SO: Acta-Paediatr-Jpn. 1996 Dec; 38(6): 695-8
AB: Recently, it has come to be accepted that the result of the tilt test is specific to neurally mediated syncope (vasovagal syncope). Only rarely is a case of paroxysmal atrial fibrillation without any organic diseases in childhood reported. A case reported here of a 14-year-old boy with neurally mediated syncope; which was complicated by paroxysmal atrial fibrillation, and which was diagnosed by performing the tilt test. Atrial fibrillation can be induced by the extraordinary stimulation of the vagal nerve during syncope. In a child, neurally mediated syncope complicated with paroxysmal atrial fibrillation has not been previously reported.
4
TI: Relationship between the pulmonary artery index and physiological properties of the pulmonary vascular bed.
AU: Senzaki-H; Kato-H; Akagi-M; Hishi-T; Yanagisawa-M
SO: Jpn-Circ-J. 1996 Jun; 60(6): 334-40
AB: BACKGROUND: To clarify the physiological significance of the pulmonary artery index (PAI), we examined the relationship between PAI and physiological properties of the pulmonary vascular bed. We also examined the limitations of PAI in practical use. METHODS AND RESULTS: We examined the relationships between PAI and pulmonary vascular resistance (Rp), pulmonary arterial compliance (Cp), and the time constant (RC) of pulmonary circulation in 50 patients with congenital heart disease with decreased pulmonary blood flow. PAI was significantly related to Cp and RC (r = 0.67, r = 0.63, respectively). These correlations became more significant when we excluded patients in whom the central pulmonary arteries were disproportionately dilatated in contrast to the peripheral pulmonary arteries (r = 0.80, r = 0.70, respectively). CONCLUSIONS: PAI reflects the state of the pulmonary vascular bed, especially when the peripheral arteries develop in proportion to the central pulmonary artery.
　
　　　　　　　　　　　　　　　　　　　　　　　　　

Edited by Toshio Hishi